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Molecule | Mesenchyme | Epithelium |Species| Gland |Stage| Expt. Methd. | Remarks | Reference
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ActR-II | 0 | 0 | Rat |Submand|16-20|ISH, to tissue|Whole mount,|Roberts,V.J. 1994
| | | | |days |section |no details. |
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ActR-II | + | Human | Not |15-17|Nothern. | |Hilden,K. 1994
| | |stated.| wks.| | |Turri,T. 1994
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ActR-IIB | + | Mouse |Submand|13-17|Northern. |Transcribed |Ritvos,O. 1995
| Not localised | | |day | | |
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ActR-IIB | 0 | ++ | Rat |Submand|16-20|ISH, to tissue|Whole mount,|Roberts,V.J. 1994
| | | | |days |section |no details. |
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ActR-IIB | + | Human | Not |15-17|Nothern. | |Hilden,K. 1994
| | |stated.| wks.| | |Turri,T. 1994
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ASGP-R1 | +++ | Rat |Submax |1 day|RT-PCR, |Falls, v.low|Mu,J.Z. 1993
| Not localised | | | pp |Northern. |by day 5. |
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bek (mRNA)| 0/+ surrounding | + basal cells? | Mouse | Not |E12.5|In-situ |cf KGFR |Orr-Urtreger,A. 1993
| epithelium | not detailed | |stated.|E14.5| | |
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CD44 | ++ V7,V8,V9. + V4,V6,V10. | Rat |Submand|E12- |RT-PCR of |Some |Weber,B. 1996
isoforms | 0/+ V2,V5. 0 V1,V3. | | |adult|variant exons |transient |
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CD44s | 0 |Transient, ++ E16| Rat |Submand|E12- |RT-PCR | |Weber,B. 1996
| | to P0 | | |adult| | |
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CD44 | 0 | + mucous acini | Rat |Submand|E12- |RT-PCR |Expressed |Weber,B. 1996
variant V6| | and ducts. | | |adult| |E18 onwards |
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EGF |Coincident with differentiative | Mouse |Submand|1-20d|Immunohist, |Androgen |Durban,E.M. 1995
-receptor |transitions in cell lineage. | | | pp |tissue sect. |independent.|
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EGF | 0 | ++ acini and | Mouse |Submand|Birth|Binding of |TGF-alpha |Gattone,V.H. 1992
-receptor | | ducts only. | | |-P10 |I125-EGF. |also binds. |
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EGF | 0 | ++ acini only. | Mouse |Submand|P10- |Binding of |Expression |Gattone,V.H. 1992
-receptor | | | | |adult|I125-EGF. |peaks at P10|
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EMA | 0 |++ epithelial | Human |Submand|Adult|Immunohist |Characterise|Okura,M. 1993
| | cells. | | | | |cells. |
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eps8 | + |+++ mainly in | Mouse |Submand|E14- |ISH to tissue |TK receptor |Avantaggiato.V. 1995
| |lobular ducts | | | E16 |sections. |substrate. |
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eps15 | 0 | 0 | Mouse |Submand|E12.5|ISH to tissue |Expressed in|Avantaggiato.V. 1995
| Detail not shown | | |E17.5|sections. |adult. |
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FGF-RI | ++ vasculature | 0 | Human |Submand|Adult|Immunohist. | |Hughes,S.E. 1993
| only. | | |Subling| |tissue sect. | |
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KGFR | 0? not detailed | +++ | Mouse |Not |E12.5|In-situ |cf bek |Orr-Urtreger,A. 1993
(mRNA)| | buds and ducts | |stated |E14.5| | |
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KGFR | 0 | 0 | Human |Subling|Adult|Ligand-IgG |See |LaRochelle,W.J. 1995
| | | | | |chimaera. |techniques. |
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c-kit | 0 | + | Human |Parotid|Adult|Immunohist, |Co-expressed|Lammie,A. 1994
| | | | | |tissue sect. |with ligand |
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PDGFRalpha| +++ | 0 | Mouse | Not |E14.5|In-situ | |Orr-Urtreger,A. 1992
(mRNA) | | | |stated.| | | |
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c-Ret | 0 | 0 | Rat |Submand|Embr.|Immunohist, | |Tsuzuki,T. 1995
| | | | | |tissue sect. | |
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c-Ret | 0 | + serous epith | Rat |Submand|Neon.|Immunohist, | |Tsuzuki,T. 1995
| | cells only | | | |tissue sect. | |
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c-Ret | 0 |+++ serous epith | Rat |Submand|2-4wk|Immunohist, | |Tsuzuki,T. 1995
| | cells only | | | pp |tissue sect | |
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c-Ret | 0 | + serous epith | Rat |Submand| 7wk |Immunohist, | |Tsuzuki,T. 1995
| | cells only | | | pp |tissue sect | |
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TbetaR-I | + | +++ | Mouse |Submand|E12 |Immunohist, |Colloc. with|Iseki,S. 1995
| | | | | &E13|tissue sect. |typeII,epith|
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TbetaR-I | 0 | +++ distal | Mouse |Submand|E13 |Immunohist, |Not in prox.|Iseki,S. 1995
| | cuboidal cells | | | &E15|tissue sect. |cells. |
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TbetaR-II | 0 | +++ | Mouse |Submand|E12 |Immunohist, |Colloc. with|Iseki,S. 1995
| | | | | &E13|tissue sect. |typeI, epith|
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TbetaR-II | 0 | +++ distally | Mouse |Submand|E13 |Immunohist, |Not in prox.|Iseki,S. 1995
| | | | | &E15|tissue sect. |cells. |
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TIA-1 | / | + | Mouse |Not |E16.5|ISH to tissue |Apoptosis? |Lowin,B. 1996
| | (0 at E14.5) | |stated |E18.4|sections. | |
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Date of last revision: 18 June 1997 - 16:12:36
dh5@holyrood.ed.ac.uk