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Molecule | Mesenchyme | Epithelium |Species| Gland |Stage| Expt. Methd. | Remarks | Reference
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Act/Inh |+/0, only in S.M | 0 | Mouse |Submand|15,17|ISH to tissue | |Ritvos,O. 1995
beta-A |surrounding ducts| | | |19dys|sections | |
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Act/Inh | 0 | 0 | Rat |Submand|16-20|ISH to tissue |No details, |Roberts,V.J. 1994
beta-A | | | | |days |sections |Whole mount.|
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Act/Inh | + | Human | Not |15-17|Northern. | |Turri,T. 1994
beta-A | not localised | |stated.| wks.| | |
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Act/Inh | 0 | +++ | Mouse |Submand|15,17|ISH to tissue |Expression |Ritvos,O. 1995
beta-B | | | | |19dys|sections |inc.wth age |
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Act/Inh | ++ expressed from E17 | Rat |Submand|E12- |ISH to tissue |No details, |Roberts,V.J. 1994
beta-B | Location not stated | | | P0|sections |Whole mount.|Roberts,V.J. 1991
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Act/Inh | ++ | Human | Not |15-17|Northern. | |Turri,T. 1994
beta-B | not localised | |stated.| wks.| | |
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EGF | 0 | ++ intralobular | Mouse |Submand|P21- |Immunohist, | Increases |Gattone,V.H. 1992
| | ducts only. | | |adult|Tissue sect | with age. |
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EGF | Expression detected, | Mouse |Submand|P2 to|RNase protect.|P15 to P22, |Durban,E.M. 1993
| not localised | | | P11 |Anti preproEGF|prepro neg. |Abstract
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EGF | ++? | Human |Submand|15-20|RT-PCR. | |Miettinen,P.J. 1993
| Not localised | | | wks | | |
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EGF | Not localised, RNA present but no | Rat |Submand|Birth|Northern, |Ab detects |Martin,M.G. 1990
| active peptide until adulthood | | |adult|RIA |active EGF |abstract.
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FGF acidic|Connective tissue| +++ ducts of | Human |Submand|Adult|Immunohist. | |Hughes,S.E. 1993
|fibroblasts only.| submand only | |Subling| |tissue sect. | |
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FGF basic | 0/+ in ECM | 0 | Rat |Submand| E18 |Immunohist. | |Gonzalez,AM. 1990
|+++ basement memb| | | | | | |
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FGF basic | 0 | 0 | Human |Submand|Adult|Immunohist. |Expressed in|Hughes,S.E. 1993
| | | |Subling| |tissue sect. |other glands|
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Inhibin- | 0 | 0 | Rat |Submand|12-20|ISH to tissue |No details, |Roberts,V.J. 1994
alpha | | | | |days |Sections |Whole mount.|
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Inhibin- | 0 | Human | Not |15-17|Northern. | |Turri,T. 1994
alpha | | |stated.| wks.| | |
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KL (c-kit | 0 | + | Human |Parotid|Adult|Immunohist, |Co-expressed|Lammie,A. 1994
ligand) | | | | | |tissue sect. |with c-kit |
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N8 | 0 | +++ | Mouse |Submand|18day|ISH to tissue | D52-like? |Chen,S.L. 1996
| | | |Subling| |sections | Byrne |
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PDGF-A | 0 | +++ | Mouse | Not |E14.5|In-situ | |Orr-Urtreger,A. 1992
(mRNA)| | | |stated.| | | |
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TGF-alpha | ++? | Human |Submand|15-20|RT-PCR, | |Miettinen,P.J. 1993
| Not localised | | | wks |Northern. | |
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TGF-beta-1|Protein surrounds|+++ expressed in | Mouse |Submand|E14.5|ISH |Active |Heine,U.I. 1987
|growing lobules. | end lobules | | | |Immunohist |growth areas|Lehnert,S.A. 1988
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TGF-beta-2| 0 | +++ | Mouse |Submand|E12.5|ISH |Prior to |Millan,F.A. 1991
| | | | | | |branching |
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TGF-beta-2| 0 | 0 | Mouse |Submand|E14.5|ISH |Branching |Millan,F.A. 1991
| | | | | | |in progress |
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TGF-beta-3| 0 | 0 | Mouse |Submand|E9.5-|ISH |No expresion|Millan,F.A. 1991
| | | | |birth| |detected. |
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Date of last revision: 07 July 1997 - 19:50:57
dh5@holyrood.ed.ac.uk