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Gene | Unind ub | Duct tip | Duct trunk | Unind MM | Stem Cells | Cond-S | Glom | Nephr | Stroma | Remark | Reference (1st auth)
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Anosmin1| | n | Y | | n | n | n | n | n | | Hardelin 1999
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Aqua- | | n | n | n | n | n | n |prox 12wk-| n | Human data. | Devuyst 1996
porin 1| | | | | | | |dist 15wk-| | |
| | | | | | | | | | |
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Aqua- | ? | Y | Y | n | n | n | n | n | n | Human data. | Devuyst 1996
porin 2| | | | | | | | | | |
| | | | | | | | | | |
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Na/K | ? | ? | Y | n | n | n | ? | Y | n | Human data. | Hennigar 1989
ATPase | | | | | | | | | | Expression |
| | | | | | | | | | odd in PKD |
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Band III| n | n | Y late | n | n | n | n | n | n | Human data | Hennigar 1989
| | | | | | | | | | |
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Carbonic| n | n | ? | n | n | n | n | Y | n | Human data. | Hennigar 1989
anhydr- | | | | | | | | | | |
ase II | | | | | | | | | | |
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CFTR | | y? | Y 12wk- | | | | |prox,Henle| | | Devuyst 1996>
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KCC1 | expressed somewhere in kidney (Northern data); functional evidence for expression in tubule cells | Gillen 1996
K-Cl co | | | | | | | | | | |
transport | | | | | | | | | |
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Na | n | n | Y | n | n | n | n | n | n | | Watanabe 1999
channel| | | | | | | | | | |
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Gene | unind ub | duct tip | duct trunk | unind MM | stem cells | cond-S | Glom | nephron | stroma | remarks | references (1st auth)
=============================================================================================================================================
acid | Y | Y | Y | y | y | ? | n | n | ? | assay by | Catayee 1964
phosph- | | | | | | | | | | activity |
atase | | | | | | | | | | |
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Gluta- | | | | Y? | Y | n | n | Y late | n | Hamster data| Oberley 1991
thione | | | | | | | | | | |
S-trans-| | | | | | | | | | |
ferase | | | | | | | | | | |
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11-beta-| | sheep day | Langlois 1995
hydroxy | somewhere in the kidney (Northern Blot and chemical assay data | E85-> |
steroid | | |
dehydro-| | |
genase | | |
type II | | |
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Heparan | y | n | n | y | Y | goes | n | n | ? | gene tag | Bullock1998
sulfate | | | | | | | | | | data |
2-sulpho| | | | | | | | | | | |
transfer| | | | | | | | | | |
ase | | | | | | | | | | |
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MMP-2 | n? | Y(lelongt|y (lelongt) | Y | Y | Y | ? | ? | ? | | Reponen 1992
| | n(Kanwar)|n (Kanwar) | | | | | | | | LeLongt 1997
| | | | | | | | | | | Kanwar 99
| | | | | | | | | | |
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MMP-9 | n? | Y | y | ? | ? | Y | ? | ? | ? | See modifier| LeLongt 1997
| | | | | | | | | | table |
| | | | | | | | | | |
| | | | | | | | | | |
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MT-1-MMP| Y? | Y | y | n | n | | | | | | Kanwar 99
| | | | | | | | | | |
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nos | | | | | | | Y late | |neurons | | Huang 1993
| | | | | | | | | E20- | | Liu 96
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Galacto-| ? | (y) | (y) | n | n | n | n? | Y | n | | Bard 1991
sidase | | | | | | | | | | |
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Protein | | Rat data | Svennilson 1995
phosphat| all isoforms expressed ubiquitously in 15 day kidneys | |
ase 1 | | | | | | | | | | |
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Protein | | Rat data | Svennilson 1995
phosphat| all isoforms expressed ubiquitously in 15 day kidneys | |
ase 2A | | | | | | | | | | |
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Rab 17 | ? | ? | ? | n | n | Y? | ? | Y | n | | Lutke 1993
GTPase | | | | | | | | | | |
===============================================================================================================================================
Gene | unind ub | duct tip | duct trunk | unind MM | stem cells | cond-S | Glom | nephron | stroma | remarks | References
==============================================================================================================================================
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Molecule| unind ub | duct tip | duct trunk | unind MM | stem cells | cond-S | Glom | nephron | stroma | remarks | references (1st auth)
=============================================================================================================================================
Brady- | | | | | | | | | | | Penshcow 1992 \ \
kinin | | | | | | | | | | |
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Brush | n | n | n | n | n | n | n | distal | n | | Miettinen 1986
border | | | | | | | | | | |
antigen | | | | | | | | | | |
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CD15 | n | n | n | n | n | n | n | proximal | | | Bard & Ross 91, Davies 94
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FANCA | | n | Y | n | n | n | n n | n | | Abu-Issa 1999
| | | | | | | | | | |
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Histamine | | | | | | | convolut-| | | Nissinen 1995
| | | | | | | | tubules | | |
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I-1 | | n | n | | Y | n | n | n | n |inhibitor of | Svennilson 1995
| | | | | | | | | |protein |
| | | | | | | | | |phosphatases |
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Kalli- | | | | | | | | Y E19- | | | Penschow 1992
krein | | | | | | | | | | |
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Polycys-| | y | y | | n | y | y | y | n | | Peters 1996
tin | | | | | | | | | | |
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PrP | ? | ? | ? | n | n | Y? | ? | Y | n | | Manson 1992
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SGP-2 | ? | (y) | (y) | n | n | Y | n | distal | | High in PKD | Harding 1991
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TIMP-3 | | | | | | | Y | Y | | low resol'n | Apte 1994
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Uromuc- | n | n | n | n | n | n | n | distal | n | | Hoyer 1974
oid | | | | | | | | | | |
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Gene | unind ub | duct tip | duct trunk | unind MM | stem cells | cond-S | Glom | nephron | stroma | remarks | References
==============================================================================================================================================
Date of last revision: 12th May 2000 Comments about the database are always welcome.
jamie.davies@ed.ac.uk